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2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010

MicroRNA-122 modulates the rhythmic expression profile of the circadian deadenylase nocturnin in mouse liver

PLoS One, Kojima S, Gatfield D, Esau CC, Green CB (2010) MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver. PLoS ONE 5(6): e11264. doi:10.1371/journal.pone.0011264

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Hidden reach of the micromanagers

BMC Biol., Linsley PS, Jackson AL.,BMC Biol. 2010 May 11;8(1):53.

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The therapeutic potential of microRNA modulation.

Discovery Medicine, Discov Med. 2010 Apr;9(47):311-8.Jackson A, Linsley PS.

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Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

Nat Biotechnol. 2010 Mar 28. [Epub ahead of print], Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Teruya-Feldstein J, Bell GW, Weinberg RA.

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Synthesis and Biophysical Evaluation of 2',4'-Constrained 2'O-Methoxyethyl and 2',4'-Constrained 2'O-Ethyl Nucleic Acid Analogues.

J Org Chem., 2010 Feb 8. [Epub ahead of print], Seth PP, Vasquez G, Allerson CA, Berdeja A, Gaus H, Kinberger GA, Prakash TP, Migawa MT, Bhat B, Swayze EE.

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Antisense Oligonucleotides Containing Conformationally Constrained 2',4'-(N-Methoxy)aminomethylene and 2',4'-Aminooxymethylene and 2'-O,4'-C-Aminomethylene Bridged Nucleoside Analogues Show Improved Potency in Animal Models.

J Med Chem., 2010 Jan 28. [Epub ahead of print], Prakash TP, Siwkowski A, Allerson CR, Migawa MT, Lee S, Gaus HJ, Black C, Seth PP, Swayze EE, Bhat B.

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Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application.

Nat Rev Drug Discov., Jackson AL, Linsley PS.,Nat Rev Drug Discov. 2010 Jan;9(1):57-67.

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