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Hidden reach of the micromanagers

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Abstract

ABSTRACT : Small interfering RNAs can trigger unintended, microRNA-like off-target effects, but the impact of these effects on functional studies has been controversial. A recent study in BMC Genomics shows that microRNA-like effects can predominate among the 'hits' of functional genomics screens.See research article http://www.biomedcentral.com/1471-2164/11/175.

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Nature Collections

Nature Collections
This collection showcases the latest papers from Nature that explore the biogenesis, biological effects in both normal and diseased cells, and therapeutic potential of miRNAs.

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