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Senior Director/Vice President Fibrosis

Job Code: Req. 306
Posted Date: 13-Jul-10

Regulus Therapeutics Inc. is a biopharmaceutical company leading the discovery and development of innovative new medicines based on microRNAs. Regulus is advancing microRNA therapeutics in several areas including hepatitis C infection, cardiovascular disease, fibrosis, oncology, immuno-inflammatory diseases, and metabolic diseases. Regulus was established in September of 2007 by Alnylam Pharmaceuticals (Nasdaq:ALNY) and Isis Pharmaceuticals (Nasdaq:ISIS) and benefits substantially from their RNA therapeutic drug expertise. In April 2008, Regulus formed an alliance with GlaxoSmithKline to explore microRNA therapeutics for immuno-inflammatory diseases. In February 2010, GSK and Regulus Therapeutics announced a new collaboration to develop and commercialize microRNA therapeutics targeting microRNA-122 for the treatment of Hepatitis C Infection. In June 2010, sanofi-aventis and Regulus Therapeutics entered into the largest strategic alliance to-date on microRNA therapeutics.

Regulus is located in Torrey Pines, California and has a seasoned executive team experienced in corporate management, business, science, drug discovery and development. Regulus' scientific advisory board consists of world-class scientists and some of the foremost authorities in the field of microRNA research.

We are currently seeking a highly motivated Senior Director/Vice President in the area of Fibrosis to be part of a unique and exciting opportunity in drug discovery. For more information, visit www.RegulusRx.com.

Requirements

Reporting to the Chief Scientific Officer, the Senior Director/Vice President, Fibrosis will be an integral member of the Regulus team and will contribute significantly to the advancement of numerous discovery and preclinical compounds into the clinic. The primary purpose of this role is to develop preclinical strategies and advance Regulus’ discovery and development of microRNA therapeutics for fibrosis to proof of concept stage in a timely and cost effective manner.

Regulus is at an exciting stage of growth and is moving towards filing its first INDs in 2011. The individual hired for this role will, therefore, have a significant impact on shaping the future of the Company.

PROFESSIONAL QUALIFICATIONS

  • Ph.D. and/or M.D. with at least 10 years of experience in the biotech/pharmaceutical industry
  • Experience working in diverse environments, including both small and large companies
  • A strong track record of scientific publications
  • Broad knowledge of fundamental fibrotic mechanisms
  • Experience with modern and classical experimental models in fibrosis
  • A demonstrated drug hunting ability and a track record of moving product candidates out of research and into the clinic
  • Great communication (both verbal and written) and leadership skills
  • The ability to work in a highly collaborative manner and thrive in a high pressure, matrix environment

PERSONAL QUALIFICATIONS

  • Above all, this leader must share the vision of Regulus and must have the passion and drive to develop and promote a cutting edge technology
  • Highly motivated with strong critical thinking and analysis skills
  • Excellent writing and language skills along with strong communication and team management skills
  • Excellent presentation skills;
  • An energetic team player who can motivate peers and enhance overall team spirit
  • A confident and strategic individual who can think outside the box and “brainstorm” in a collegial manner;
  • An open minded individual with the ability to influence others without needing absolute control
  • An innovative, driven and effective person with a “can do” attitude
  • A person who can operate effectively in a small company and manage with minimal internal resources
  • A goal-oriented person who can plan for the long-term and execute stated objectives

Excellent salary and benefits package offered.

For immediate consideration, please apply to careers@regulusrx.com

You can visit our website to find out more about our company and culture: www.RegulusRx.com.

Reference job code: 306

NO PHONE CALLS PLEASE.  PRINCIPALS ONLY

Regulus Therapeutics, Inc., is proud to be an EEO Employer

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